Hierarchy Settings for Data restriction

Hello Team,

I have specific customer requirement for data access configuration.

Client have Regions(All, West, South, North, central)  and more than 18 different business groups(Lets consider it as a BG1, BG2, BG3....BG20).

Now, each user can have multiple access of business group. They are using opportunity module and each opportunity will be consist of one business Group.

E.g. User A is working in North region and looking after only BG1, BG2 & BG5.

Another user B is working in West Region and looking after BG5, BG 6, BG9

User C is Looking country level and have only access of BG10

User D  is working in East region having access to view all opportunity (All BG)

In above case, User A, B, C and D can view opportunities according to combination of region and Business group

Please help me to understand how i can configure this level of data restriction in CRM

Thanks in Advance