unable to debug CRM on-premise after creating multiple organizations

I was able to successfully debug my plugins on on-premise CRM by attaching processes to visual studio earlier when i had created just 1 organization.

I register my plugins in database, in non-sandbox mode. I also add the assembly in pdb file in /assembly/bin directory of CRM server.

Then do an IISRESET.

Then, attach both CrmAsyncService process and w3wp process.

But after i created multiple organizations, i am unable to do so now.

Do i need to something elase to get it working?